| Ders Adı | Kodu | Yarıyıl | T+U Saat | Kredi | AKTS |
|---|---|---|---|---|---|
| Energy Metabolısm | TBK 511 | 0 | 3 + 1 | 4 | 6 |
| Ön Koşul Dersleri | |
| Önerilen Seçmeli Dersler | |
| Dersin Dili | Türkçe |
| Dersin Seviyesi | YUKSEK_LISANS |
| Dersin Türü | Seçmeli |
| Dersin Koordinatörü | Prof.Dr. MEHMET AKDOĞAN |
| Dersi Verenler | |
| Dersin Yardımcıları | |
| Dersin Kategorisi | Alanına Uygun Temel Öğretim |
| Dersin Amacı | Giving information about the energy metabolism in living systems |
| Dersin İçeriği | Bioenergetics principles and laws of thermodynamics, free energy (G) change, the relationship between free energy change and equilibrium constant, standard and free energy changes in non-standard conditions, high energy compounds and phosphoryl group transfer, phosphodiester bond and ATP, Sequential reactions and additivity of the free energy, biological oxidation-reduction reactions, the standard electrode potential and Nerns equation, FAD and NAD (P) related to oxidation-reduction reactions, electron transport chain and inhibitors, entry and hypotheses to oxidative phosphorylation, metabolism and ATP production: glycolysis the oxidation of fatty acids and ATP production. |
| # | Ders Öğrenme Çıktıları | Öğretim Yöntemleri | Ölçme Yöntemleri |
|---|---|---|---|
| 1 | Learning the energy metabolism and related calculations | Lecture, | Testing, Homework, |
| 2 | Lecture, Question-Answer, Discussion, | Testing, |
| Hafta | Ders Konuları | Ön Hazırlık |
|---|---|---|
| 1 | Definition and types of energy | |
| 2 | System, the environment and the universe; open, closed and isolated systems | |
| 3 | The laws of thermodynamics and metabolism | |
| 4 | Endothermic, exothermic; endergonik and Exergonic reactions | |
| 5 | Coupling of exergonic reaction with endergonik reaction | |
| 6 | ATP and other high energy chemical bonds containing biomolecules | |
| 7 | Midterm exam | |
| 8 | The relationship between the free energy and Enthalpy, entropy; Gibbs free energy equation | |
| 9 | the relationship between free energy and product / substrate concentration ratio | |
| 10 | Bioenergetics and high energy molecules | |
| 11 | High-energy compounds and energy relationships | |
| 12 | The relationship between free energy and equilibrium constant | |
| 13 | Free energy change and oxidation-reduction potential | |
| 14 | Enzymes and coenzymes which are working in the oxidation-reduction reaction of |
| Kaynaklar | |
|---|---|
| Ders Notu | 1. Lawrence A. Kaplan, Amadeo J. Pesce Teory Analysis Correlations Clinical Chemistry. Mosby ELSEVIER, Indiana, 2010. |
| Ders Kaynakları | |
| Sıra | Program Çıktıları | Katkı Düzeyi | |||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Sutudent has detailed biomolecules and metabolic information; uses this information and develops | X | |||||
| 2 | Knows and uses the specific equipment and tools of Biochemistry | X | |||||
| 3 | Knows and uses basic laboratory knowledge such as Laboratory safety, biochemical methods | X | |||||
| 4 | Reachs their printed and electronic information sources and follows the developments in the Biochemistry and related fields | X | |||||
| 5 | Theoretical knowledge and critical thinking skills are applied to specific work areas to plan related experiments | X | |||||
| 6 | present a seminar on a topic of current biochemistry | X | |||||
| 7 | Reads, understands, interprets, and criticizes an article in the field of biochemistry, | X | |||||
| Değerlendirme Sistemi | |
|---|---|
| Yarıyıl Çalışmaları | Katkı Oranı |
| 1. Ara Sınav | 70 |
| 1. Ödev | 20 |
| 1. Kısa Sınav | 10 |
| Toplam | 100 |
| 1. Final | 50 |
| 1. Yıl İçinin Başarıya | 50 |
| Toplam | 100 |
| AKTS - İş Yükü Etkinlik | Sayı | Süre (Saat) | Toplam İş Yükü (Saat) |
|---|---|---|---|
| Course Duration (Including the exam week: 16x Total course hours) | 16 | 2 | 32 |
| Hours for off-the-classroom study (Pre-study, practice) | 16 | 6 | 96 |
| Mid-terms | 1 | 6 | 6 |
| Final examination | 1 | 10 | 10 |
| Toplam İş Yükü | 144 | ||
| Toplam İş Yükü / 25 (Saat) | 5,76 | ||
| Dersin AKTS Kredisi | 6 | ||