Course Name Code Semester T+U Hours Credit ECTS
Structure Activity Relationship Of Organic Molecules KIM 595 0 3 + 0 3 6
Precondition Courses <p>None</p>
Recommended Optional Courses <p>None</p>
Course Language Turkish
Course Level yuksek_lisans
Course Type Optional
Course Coordinator Doç.Dr. FATİH SÖNMEZ
Course Lecturers
Course Assistants
Course Category Field Proper Education
Course Objective

Since the beginning of organic molecules in the biological environment to accumulate information about the behavior of the structure-activity relationships of concepts increasingly gained importance and it has now become a desirable and sought work in scientific publications.
  In this context, it synthesized make predictions about having to show what kind of biological activity of new molecules, is to gain the ability to make a comment about the relationship between the activities in which the organic molecules.

Course Content

Structure activity relationship; Screening and identification of biologically active organic molecules; The functional groups at organic compounds showing activity and effect mechanisms of these groups; Biological effects of screening method; Chemical variation method; Screening of various publications in the literature in recent years and investigation of structure-activity relationships in these publications.

# Course Learning Outcomes Teaching Methods Assessment Methods
1 To know the concept of structure-activity relationship Lecture, Question-Answer, Discussion, Drilland Practice, Testing, Oral Exam, Homework,
2 To derivatizate new molecules suitable to the structure-activity relationships Lecture, Question-Answer, Discussion, Drilland Practice, Testing, Oral Exam, Homework, Performance Task,
3 To interpret the structure-activity relationship Lecture, Question-Answer, Discussion, Drilland Practice, Testing, Oral Exam, Homework, Performance Task,
Week Course Topics Preliminary Preparation
1 Structure-activity relationship concept Compilation of resources and articles and presentation
2 Screening and identification of biologically active organic molecules Compilation of resources and articles and presentation
3 Screening and identification of biologically active organic molecules Compilation of resources and articles and presentation
4 Functional groups which are active in organic compounds and their mechanisms of action Compilation of resources and articles and presentation
5 Functional groups which are active in organic compounds and their mechanisms of action Compilation of resources and articles and presentation
6 Functional groups which are active in organic compounds and their mechanisms of action Compilation of resources and articles and presentation
7 Screening method of biological effect Compilation of resources and articles and presentation
8 Screening method of biological effect Compilation of resources and articles and presentation
9 Midterm exam
10 Chemical diversity method Compilation of resources and articles and presentation
11 Chemical diversity method Compilation of resources and articles and presentation
12 Screening of various publications and reviewing structure-activity relations in the literature in recent years Compilation of resources and articles and presentation
13 Screening of various publications and reviewing structure-activity relations in the literature in recent years Compilation of resources and articles and presentation
14 Screening of various publications and reviewing structure-activity relations in the literature in recent years Compilation of resources and articles and presentation
Resources
Course Notes <p>[1] Şener, E.A., Yal&ccedil;ın, İ., &ldquo;Kantitatif Yapı-Etki İlişkileri Analizleri&rdquo;. Ankara &Uuml;niversitesi Eczacılık Fak&uuml;ltesi Yayınları, 2003.</p>
Course Resources

[2] Nicolaou, K.C., Montagnon, T., ‘Molecules that changed the world’. Wiley-VCH, 2008.

[3] Balcı, M., ‘Organik Kimya Reaksiyon Mekanizmaları’. ODTÜ Yayınları, 2008.

[4] Periodical Publications

Order Program Outcomes Level of Contribution
1 2 3 4 5
1 In addition to expanding and making deeper the knowledge established on undergraduate education in a same or different area, reaches the knowledge by doing research and also improves his or her knowledge to the expertise level by doing evaluation and practice. X
2 Utilizing incomplete or limited data in his or her study area expands the knowledge by experimental methods and use those obtained knowledge by scientific, social and ethical responsibility. X
3 - Constructs a problem with his/her adviser and develops a solution method and by evaluating the results apply them if it is necessary in his/ her area. X
4 -Transfer the current developments and his/her studies to the other related or nonrelated groups as written, orally and visually. X
5 - Develops new strategic approach and produces solutions in unexpected and complicated situations in his or her area of practice. X
6 - Develops strategic and practice plans and evaluates the obtained results within the framework of quality process in his or her study area. X
7 - Has written communication ability in one of well known foreign languages (“European Language Portfolio Global Scale”, Level A1).
8 -Has knowledge for software and hardware about computers and uses data processing. X
9 Protecting scientific, social, and ethical values, teaches and controls these values in the steps of collection, evaluation and announcement of data in the international arena. X
10 - Applies his or her digested knowledge and problem solving ability in advanced studies. X
Evaluation System
Semester Studies Contribution Rate
1. Ara Sınav 70
1. Ödev 15
1. Performans Görevi (Seminer) 15
Total 100
1. Yıl İçinin Başarıya 50
1. Final 50
Total 100
ECTS - Workload Activity Quantity Time (Hours) Total Workload (Hours)
Course Duration (Including the exam week: 16x Total course hours) 16 3 48
Hours for off-the-classroom study (Pre-study, practice) 16 3 48
Mid-terms 1 15 15
Assignment 1 15 15
Performance Task (Seminar) 1 10 10
Final examination 1 20 20
Total Workload 156
Total Workload / 25 (Hours) 6.24
dersAKTSKredisi 6