Course Name Code Semester T+U Hours Credit ECTS
Cancer Molecular Biology BMM 528 0 3 + 0 3 6
Precondition Courses
Recommended Optional Courses
Course Language Turkish
Course Level yuksek_lisans
Course Type Optional
Course Coordinator Doç.Dr. GAMZE GÜNEY ESKİLER
Course Lecturers Doç.Dr. GAMZE GÜNEY ESKİLER,
Course Assistants
Course Category Field Proper Education
Course Objective

Learning cancer cell biology at the molecular level

Course Content

In the content of this course; Genetic and epigenetic changes that occur in cancer, cancer-causing viruses, oncogenes and proteins, tumor suppressor genes and their characteristics features, cancer types, metastasis, carcinogenic substances, molecular mechanisms specific to cancer types, cancer treatment methods and their relationship with molecular signaling pathways and innovative treatment methods

# Course Learning Outcomes Teaching Methods Assessment Methods
1 Describe cancer cell biology Lecture, Question-Answer, Discussion, Testing, Homework,
2 Understand the role of genetic anomalies in cancer development Discussion, Question-Answer, Lecture, Homework, Testing,
3 Explain epigenetic and genetic changes in tumor development Discussion, Question-Answer, Lecture, Homework, Testing,
4 Explain tumor suppressor genes and their molecular mechanisms Discussion, Question-Answer, Lecture, Homework, Testing,
5 Describe the types of cell death Discussion, Question-Answer, Lecture, Homework, Testing,
6 Discussion, Question-Answer, Lecture, Homework, Testing,
Week Course Topics Preliminary Preparation
1 Cell and its properties
2 Cell cycle and control
3 Cancer and its characteristics
4 The role of genes in cancer development
5 Mechanisms of transformation of protoncogenes into oncogenes
6 Cancer and epigenetic changes
7 Carcinogens and Oncogenic Viruses
8 Metastasis and angiogenesis
9 Cell death types
10 Programmed cell death
11 Hereditary cancer types and their molecular mechanisms
12 Cancer and gene therapy
13 Cancer and immunotherapy
14 Current approaches in cancer treatment
Course Notes
Course Resources

Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Keith Roberts, Peter Walter. Molecular Biology of the Cell (Ed.6th), Garland Science, USA, 2014.

Tom Strachan, Andrew Read, Human Molecular Genetics (Ed.4th), 2010.

The Biology of Cancer 2nd edition by Weinberg, Robert A. (2013)

Order Program Outcomes Level of Contribution
1 2 3 4 5
1 An understanding of integrated knowledge of science and engineering in the biomedical issues. X
2 The capability to apply advanced mathematics to solve the problems at the interface of engineering and biology
3 The ability to carry out measurements on living systems and interpret the obtained data X
4 An ability to function on multi-disciplinary teams X
5 Addressing the problems associated with both living and non-living materials and systems X
6 Proficiency in the use of modern techniques, tools, procedures, and knowledge useful in the definition and solution of problems in biomedical engineering area.
Evaluation System
Semester Studies Contribution Rate
1. Ara Sınav 50
1. Ödev 50
Total 100
1. Yıl İçinin Başarıya 60
1. Final 40
Total 100
ECTS - Workload Activity Quantity Time (Hours) Total Workload (Hours)
Course Duration (Including the exam week: 16x Total course hours) 16 3 48
Hours for off-the-classroom study (Pre-study, practice) 16 2 32
Mid-terms 1 25 25
Assignment 1 20 20
Final examination 1 25 25
Total Workload 150
Total Workload / 25 (Hours) 6
dersAKTSKredisi 6