Course Name Code Semester T+U Hours Credit ECTS
Energy Metabolism TBK 511 0 3 + 1 4 6
Precondition Courses
Recommended Optional Courses
Course Language Turkish
Course Level yuksek_lisans
Course Type Optional
Course Coordinator Prof.Dr. MEHMET AKDOĞAN
Course Lecturers
Course Assistants
Course Category Available Basic Education in the Field
Course Objective

Giving information about the energy metabolism in living systems

Course Content

Bioenergetics principles and laws of thermodynamics, free energy (G) change, the relationship between free energy change and equilibrium constant, standard and free energy changes in non-standard conditions, high energy compounds and phosphoryl group transfer, phosphodiester bond and ATP, Sequential reactions and additivity of the free energy, biological oxidation-reduction reactions, the standard electrode potential and Nerns equation, FAD and NAD (P) related to oxidation-reduction reactions, electron transport chain and inhibitors, entry and hypotheses to oxidative phosphorylation, metabolism and ATP production: glycolysis the oxidation of fatty acids and ATP production.

# Course Learning Outcomes Teaching Methods Assessment Methods
1 Learning the energy metabolism and related calculations Lecture, Testing, Homework,
2 Lecture, Question-Answer, Discussion, Testing,
Week Course Topics Preliminary Preparation
1 Definition and types of energy
2 System, the environment and the universe; open, closed and isolated systems
3 The laws of thermodynamics and metabolism
4 Endothermic, exothermic; endergonik and Exergonic reactions
5 Coupling of exergonic reaction with endergonik reaction
6 ATP and other high energy chemical bonds containing biomolecules
7 Midterm exam
8 The relationship between the free energy and Enthalpy, entropy; Gibbs free energy equation
9 the relationship between free energy and product / substrate concentration ratio
10 Bioenergetics and high energy molecules
11 High-energy compounds and energy relationships
12 The relationship between free energy and equilibrium constant
13 Free energy change and oxidation-reduction potential
14 Enzymes and coenzymes which are working in the oxidation-reduction reaction of
Course Notes <p>1. Lawrence A. Kaplan, Amadeo J. Pesce Teory Analysis Correlations Clinical Chemistry. Mosby ELSEVIER, Indiana, 2010.<br /> 2. Rex Montgomery, Thomas W. Conway, Arthur A. Spector Biyokimya olgu sunumlu yaklaşım. &Ccedil;eviri edit&ouml;r&uuml;: Nilg&uuml;n Altan Palme Yayıncılık. Ankara, 2000.<br /> 3. Robert K. Murray, Daryl K. Granner, Peter A. Mayes, Victor V. Rodwell Harper biyokimya, &Ccedil;eviri edit&ouml;r&uuml;: Nurten Dikmen, Tuncay &Ouml;zg&uuml;nen. Nobel Tıp Kitabevi Ankara, 2004<br /> 4. Robert K Murray, David A. BENDER. Harper&rsquo;s Illustrated biochemistry 28TH, Mc Graw Hill Toronto 2009</p>
Course Resources
Order Program Outcomes Level of Contribution
1 2 3 4 5
1 Sutudent has detailed biomolecules and metabolic information; uses this information and develops X
2 Knows and uses the specific equipment and tools of Biochemistry X
3 Knows and uses basic laboratory knowledge such as Laboratory safety, biochemical methods X
4 Reachs their printed and electronic information sources and follows the developments in the Biochemistry and related fields X
5 Theoretical knowledge and critical thinking skills are applied to specific work areas to plan related experiments X
6 present a seminar on a topic of current biochemistry X
7 Reads, understands, interprets, and criticizes an article in the field of biochemistry, X
Evaluation System
Semester Studies Contribution Rate
1. Ara Sınav 70
1. Ödev 20
1. Kısa Sınav 10
Total 100
1. Final 50
1. Yıl İçinin Başarıya 50
Total 100
ECTS - Workload Activity Quantity Time (Hours) Total Workload (Hours)
Course Duration (Including the exam week: 16x Total course hours) 16 2 32
Hours for off-the-classroom study (Pre-study, practice) 16 6 96
Mid-terms 1 6 6
Final examination 1 10 10
Total Workload 144
Total Workload / 25 (Hours) 5.76
dersAKTSKredisi 6