Ders Adı | Kodu | Yarıyıl | T+U Saat | Kredi | AKTS |
---|---|---|---|---|---|
Organo Drug Synthesıs | KIM 586 | 0 | 3 + 0 | 3 | 6 |
Ön Koşul Dersleri | |
Önerilen Seçmeli Dersler | |
Dersin Dili | Türkçe |
Dersin Seviyesi | YUKSEK_LISANS |
Dersin Türü | Seçmeli |
Dersin Koordinatörü | Prof.Dr. MUSTAFA ZENGİN |
Dersi Verenler | Prof.Dr. MUSTAFA ZENGİN, |
Dersin Yardımcıları | |
Dersin Kategorisi | Diğer |
Dersin Amacı | Synthetic Organic compounds are very important for the drug synthesis recently. Synthesize of some natural products which are essential for human healthy are getting inevitable especially when the world population increases are considered. Most of the groups which study on synthetic organic chemistry tend to this field to synthesize compounds to be likely drug. In this lecture, general strategies on multistep synthesis of these compounds will be handled. |
Dersin İçeriği | Introduction to reactions. Coupling reactions, palladyum chemistry, Karashi Reactions Stille Reactions Heck Reactions Sonogashira Reactions Suzuki Reactions, Dipolar addition, Indole and Reactions, Carbazole and Reactions, Synhesis of Peniciline, Isoquinoline reactions, Suberan derivatives and Reactions, Synthesis of Hirsutene, Synthesis will be discussed. |
# | Ders Öğrenme Çıktıları | Öğretim Yöntemleri | Ölçme Yöntemleri |
---|---|---|---|
1 | He/she knows structure of drug active materials | Lecture, | Testing, |
2 | He/she classificatives of drug materials | Lecture, | Testing, |
3 | He/she comprehends synthesis of drug active metarials | Lecture, | Testing, |
4 | He/she understands and comments reaction mecanism | Lecture, | Testing, |
5 | He/she comprehends isolation methods of synthesized compounds | Lecture, | Testing, |
6 | Developing of predisposition to self-confidence to work with groups | Lecture, | Testing, |
Hafta | Ders Konuları | Ön Hazırlık |
---|---|---|
1 | Introduction to reactions. | |
2 | Coupling reactions | |
3 | Karashi Reactions Stille Reactions Heck Reactions | |
4 | Reactions Sonogashira Reactions Suzuki Reactions, Dipolar addition | |
5 | Indole and Reactions | |
6 | Carbazole and Reactions | |
7 | Synhesis of Peniciline | |
8 | Synhesis of Peniciline | |
9 | Midterm Exam | |
10 | Isoquinoline reactions | |
11 | Suberan derivatives and Reactions | |
12 | Synthesis of Hirsutene | |
13 | Synthesis of Hirsutene | |
14 | Synthesis of Capnellene |
Kaynaklar | |
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Ders Notu | |
Ders Kaynakları |
Sıra | Program Çıktıları | Katkı Düzeyi | |||||
---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | |||
1 | In addition to expanding and making deeper the knowledge established on undergraduate education in a same or different area, reaches the knowledge by doing research and also improves his or her knowledge to the expertise level by doing evaluation and practice. | X | |||||
1 | In addition to expanding and making deeper the knowledge established on undergraduate education in a same or different area, reaches the knowledge by doing research and also improves his or her knowledge to the expertise level by doing evaluation and practice. | X | |||||
2 | Utilizing incomplete or limited data in his or her study area expands the knowledge by experimental methods and use those obtained knowledge by scientific, social and ethical responsibility. | X | |||||
2 | Utilizing incomplete or limited data in his or her study area expands the knowledge by experimental methods and use those obtained knowledge by scientific, social and ethical responsibility. | X | |||||
3 | - Constructs a problem with his/her adviser and develops a solution method and by evaluating the results apply them if it is necessary in his/ her area. | X | |||||
3 | - Constructs a problem with his/her adviser and develops a solution method and by evaluating the results apply them if it is necessary in his/ her area. | X | |||||
4 | -Transfer the current developments and his/her studies to the other related or nonrelated groups as written, orally and visually. | X | |||||
4 | -Transfer the current developments and his/her studies to the other related or nonrelated groups as written, orally and visually. | X | |||||
5 | - Develops new strategic approach and produces solutions in unexpected and complicated situations in his or her area of practice. | X | |||||
5 | - Develops new strategic approach and produces solutions in unexpected and complicated situations in his or her area of practice. | X | |||||
6 | - Develops strategic and practice plans and evaluates the obtained results within the framework of quality process in his or her study area. | X | |||||
6 | - Develops strategic and practice plans and evaluates the obtained results within the framework of quality process in his or her study area. | X | |||||
7 | - Has written communication ability in one of well known foreign languages (“European Language Portfolio Global Scale”, Level A1). | ||||||
7 | - Has written communication ability in one of well known foreign languages (“European Language Portfolio Global Scale”, Level A1). | ||||||
8 | -Has knowledge for software and hardware about computers and uses data processing. | ||||||
8 | -Has knowledge for software and hardware about computers and uses data processing. | ||||||
9 | Protecting scientific, social, and ethical values, teaches and controls these values in the steps of collection, evaluation and announcement of data in the international arena. | ||||||
9 | Protecting scientific, social, and ethical values, teaches and controls these values in the steps of collection, evaluation and announcement of data in the international arena. | ||||||
10 | - Applies his or her digested knowledge and problem solving ability in advanced studies. | X |
Değerlendirme Sistemi | |
---|---|
Yarıyıl Çalışmaları | Katkı Oranı |
1. Ödev | 15 |
1. Ara Sınav | 60 |
2. Ödev | 15 |
3. Ödev | 10 |
Toplam | 100 |
1. Yıl İçinin Başarıya | 50 |
1. Final | 50 |
Toplam | 100 |
AKTS - İş Yükü Etkinlik | Sayı | Süre (Saat) | Toplam İş Yükü (Saat) |
---|---|---|---|
Course Duration (Including the exam week: 16x Total course hours) | 16 | 3 | 48 |
Hours for off-the-classroom study (Pre-study, practice) | 16 | 3 | 48 |
Mid-terms | 1 | 15 | 15 |
Assignment | 1 | 10 | 10 |
Performance Task (Seminar) | 1 | 10 | 10 |
Final examination | 1 | 20 | 20 |
Toplam İş Yükü | 151 | ||
Toplam İş Yükü / 25 (Saat) | 6,04 | ||
Dersin AKTS Kredisi | 6 |