Course Name Code Semester T+U Hours Credit ECTS
Heterocyclic Reactions I KIM 584 0 3 + 0 3 6
Precondition Courses
Recommended Optional Courses
Course Language Turkish
Course Level yuksek_lisans
Course Type Optional
Course Coordinator Doç.Dr. HAYRİYE GENÇ BİLGİÇLİ
Course Lecturers Doç.Dr. HAYRİYE GENÇ BİLGİÇLİ,
Course Assistants
Course Category
Course Objective This lesson is designed for graduate students who wish to improve the fundamental of heterocyclic chemistry and obtain a better grasp of the reactivity of heteroaromatic systems.
Course Content General information including structure, physical properties, common synthesis methods about heterocycles. Investigation of synthesis and reactions of Furans, Thiophenes, Pyrroles, Indoles, Triazoles, Imidazoles, Quinolones, Pyrans etc.
# Course Learning Outcomes Teaching Methods Assessment Methods
1 He/she comprehends the structures of heterocyclic compounds used extensively in drug industry and other industrial branches Lecture, Testing,
2 He/she classifies heterocyclic compounds Lecture, Testing,
3 He/she designs synthesis for heterocyclic compounds Lecture, Testing,
4 He/she comprehends isolation methods of synthesized compounds Lecture, Testing,
5 He/she examines heterocyclic compounds as mechanistic Lecture, Testing,
6 He/she comprehends biological properties of heterocyclic compounds Lecture, Testing,
Week Course Topics Preliminary Preparation
1 Introduction Examples from recent articles
2 The structure of heterocycles [1] reference 1-4
3 General methods for the synthesis of heterocycles [2] reference 1-9
4 Furans [1] reference 61-86
5 Thiphenes [1] reference 90-107
6 Pyrolles [1] reference 108-124
7 Pyridines [2] reference 1-9
8 Pyridines [1] reference 345-380
9 Midterm Exam
10 Quinolines and Isoquinolines [2] reference 46-52
11 Indoles [2] reference 53-60
12 Five-membered ring heterocycles with three or four heteroatoms [2] reference 61-66
13 Six-membered ring heterocycles containing one hydrogen atom [2] reference 67-72
14 Sample problems with solution Recent articles about total synthesis
Resources
Course Notes [1] Eicher, Theophil, Siegfried Hauptmann, and Andreas Speicher. The Chemistry of Heterocycles: Structures, Reactions, Synthesis, and Applications 3rd. John Wiley & Sons, 2013.<br>[2] Davies, David T. Aromatic heterocyclic chemistry. De Boeck Supérieur, 1997.
Course Resources Recent articles
Order Program Outcomes Level of Contribution
1 2 3 4 5
1 In addition to expanding and making deeper the knowledge established on undergraduate education in a same or different area, reaches the knowledge by doing research and also improves his or her knowledge to the expertise level by doing evaluation and practice. X
1 In addition to expanding and making deeper the knowledge established on undergraduate education in a same or different area, reaches the knowledge by doing research and also improves his or her knowledge to the expertise level by doing evaluation and practice. X
2 Utilizing incomplete or limited data in his or her study area expands the knowledge by experimental methods and use those obtained knowledge by scientific, social and ethical responsibility. X
2 Utilizing incomplete or limited data in his or her study area expands the knowledge by experimental methods and use those obtained knowledge by scientific, social and ethical responsibility. X
3 - Constructs a problem with his/her adviser and develops a solution method and by evaluating the results apply them if it is necessary in his/ her area. X
3 - Constructs a problem with his/her adviser and develops a solution method and by evaluating the results apply them if it is necessary in his/ her area. X
4 -Transfer the current developments and his/her studies to the other related or nonrelated groups as written, orally and visually. X
4 -Transfer the current developments and his/her studies to the other related or nonrelated groups as written, orally and visually.
5 - Develops new strategic approach and produces solutions in unexpected and complicated situations in his or her area of practice. X
5 - Develops new strategic approach and produces solutions in unexpected and complicated situations in his or her area of practice.
6 - Develops strategic and practice plans and evaluates the obtained results within the framework of quality process in his or her study area.
6 - Develops strategic and practice plans and evaluates the obtained results within the framework of quality process in his or her study area. X
7 - Has written communication ability in one of well known foreign languages (“European Language Portfolio Global Scale”, Level A1). X
7 - Has written communication ability in one of well known foreign languages (“European Language Portfolio Global Scale”, Level A1).
8 -Has knowledge for software and hardware about computers and uses data processing.
8 -Has knowledge for software and hardware about computers and uses data processing. X
9 Protecting scientific, social, and ethical values, teaches and controls these values in the steps of collection, evaluation and announcement of data in the international arena. X
9 Protecting scientific, social, and ethical values, teaches and controls these values in the steps of collection, evaluation and announcement of data in the international arena. X
10 - Applies his or her digested knowledge and problem solving ability in advanced studies. X
Evaluation System
Semester Studies Contribution Rate
1. Ödev 10
1. Ara Sınav 70
1. Kısa Sınav 20
Total 100
1. Yıl İçinin Başarıya 50
1. Final 50
Total 100
ECTS - Workload Activity Quantity Time (Hours) Total Workload (Hours)
Course Duration (Including the exam week: 16x Total course hours) 16 3 48
Hours for off-the-classroom study (Pre-study, practice) 16 3 48
Mid-terms 1 15 15
Assignment 1 10 10
Performance Task (Seminar) 1 10 10
Final examination 1 20 20
Total Workload 151
Total Workload / 25 (Hours) 6.04
dersAKTSKredisi 6