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Ders Tanımı

Ders Kodu Yarıyıl T+U Saat Kredi AKTS
ORGANO DRUG SYNTHESIS KIM 586 0 3 + 0 3 6
Ön Koşul Dersleri
Önerilen Seçmeli Dersler
Dersin Dili Türkçe
Dersin Seviyesi Yüksek Lisans
Dersin Türü SECMELI
Dersin Koordinatörü Prof.Dr. MUSTAFA ZENGİN
Dersi Verenler
Dersin Yardımcıları
Dersin Kategorisi
Dersin Amacı
Synthetic Organic compounds are very important for the drug synthesis recently. Synthesize of some natural products which are essential for human healthy are getting inevitable especially when the world population increases are considered. Most of the groups which study on synthetic organic chemistry tend to this field to synthesize compounds to be likely drug.
In this lecture, general strategies on multistep synthesis of these compounds will be handled.
Dersin İçeriği
Introduction to reactions. Coupling reactions, palladyum chemistry, Karashi Reactions Stille Reactions Heck Reactions Sonogashira Reactions Suzuki Reactions, Dipolar addition, Indole and Reactions, Carbazole and Reactions, Synhesis of Peniciline, Isoquinoline reactions, Suberan derivatives and Reactions, Synthesis of Hirsutene, Synthesis will be discussed.
Dersin Öğrenme Çıktıları Öğretim Yöntemleri Ölçme Yöntemleri
1 - He/she knows structure of drug active materials 1 - A -
2 - He/she classificatives of drug materials 1 - A -
3 - He/she comprehends synthesis of drug active metarials 1 - A -
4 - He/she understands and comments reaction mecanism 1 - A -
5 - He/she comprehends isolation methods of synthesized compounds 1 - A -
6 - Developing of predisposition to self-confidence to work with groups 1 - A -
Öğretim Yöntemleri: 1:Lecture
Ölçme Yöntemleri: A:Testing

Ders Akışı

Hafta Konular ÖnHazırlık
1 Introduction to reactions.
2 Coupling reactions
3 Karashi Reactions Stille Reactions Heck Reactions
4 Reactions Sonogashira Reactions Suzuki Reactions, Dipolar addition
5 Indole and Reactions
6 Carbazole and Reactions
7 Synhesis of Peniciline
8 Synhesis of Peniciline
9 Midterm Exam
10 Isoquinoline reactions
11 Suberan derivatives and Reactions
12 Synthesis of Hirsutene
13 Synthesis of Hirsutene
14 Synthesis of Capnellene

Kaynaklar

Ders Notu
Ders Kaynakları

Döküman Paylaşımı


Dersin Program Çıktılarına Katkısı

No Program Öğrenme Çıktıları KatkıDüzeyi
1 2 3 4 5
1 In addition to expanding and making deeper the knowledge established on undergraduate education in a same or different area, reaches the knowledge by doing research and also improves his or her knowledge to the expertise level by doing evaluation and practice. X
2 Utilizing incomplete or limited data in his or her study area expands the knowledge by experimental methods and use those obtained knowledge by scientific, social and ethical responsibility. X
3 - Constructs a problem with his/her adviser and develops a solution method and by evaluating the results apply them if it is necessary in his/ her area. X
4 -Transfer the current developments and his/her studies to the other related or nonrelated groups as written, orally and visually. X
5 - Develops new strategic approach and produces solutions in unexpected and complicated situations in his or her area of practice. X
6 - Develops strategic and practice plans and evaluates the obtained results within the framework of quality process in his or her study area. X
7 - Has written communication ability in one of well known foreign languages (“European Language Portfolio Global Scale”, Level A1).
8 -Has knowledge for software and hardware about computers and uses data processing.
9 Protecting scientific, social, and ethical values, teaches and controls these values in the steps of collection, evaluation and announcement of data in the international arena.
10 In addition to expanding and making deeper the knowledge established on undergraduate education in a same or different area, reaches the knowledge by doing research and also improves his or her knowledge to the expertise level by doing evaluation and practice. X
11 Utilizing incomplete or limited data in his or her study area expands the knowledge by experimental methods and use those obtained knowledge by scientific, social and ethical responsibility. X
12 - Constructs a problem with his/her adviser and develops a solution method and by evaluating the results apply them if it is necessary in his/ her area. X
13 -Transfer the current developments and his/her studies to the other related or nonrelated groups as written, orally and visually. X
14 - Develops new strategic approach and produces solutions in unexpected and complicated situations in his or her area of practice. X
15 - Develops strategic and practice plans and evaluates the obtained results within the framework of quality process in his or her study area. X
16 - Has written communication ability in one of well known foreign languages (“European Language Portfolio Global Scale”, Level A1).
17 -Has knowledge for software and hardware about computers and uses data processing.
18 Protecting scientific, social, and ethical values, teaches and controls these values in the steps of collection, evaluation and announcement of data in the international arena.
19 - Applies his or her digested knowledge and problem solving ability in advanced studies. X

Değerlendirme Sistemi

YARIYIL İÇİ ÇALIŞMALARI SIRA KATKI YÜZDESİ
AraSinav 1 70
Odev 1 15
PerformansGoreviSeminer 1 15
Toplam 100
Yıliçinin Başarıya Oranı 50
Finalin Başarıya Oranı 50
Toplam 100

AKTS - İş Yükü

Etkinlik Sayısı Süresi(Saat) Toplam İş yükü(Saat)
Course Duration (Including the exam week: 16x Total course hours) 16 3 48
Hours for off-the-classroom study (Pre-study, practice) 16 3 48
Mid-terms 1 15 15
Assignment 1 10 10
Performance Task (Seminar) 1 10 10
Final examination 1 20 20
Toplam İş Yükü 151
Toplam İş Yükü /25(s) 6.04
Dersin AKTS Kredisi 6.04
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