Ders Bilgileri

#### Ders Tanımı

Ders Kodu Yarıyıl T+U Saat Kredi AKTS
ENERGY METABOLISM TBK 511 0 3 + 1 4 6
 Dersin Dili Türkçe Dersin Seviyesi Yüksek Lisans Dersin Türü SECMELI Dersin Koordinatörü Prof.Dr. MEHMET AKDOĞAN Dersi Verenler Dersin Yardımcıları Dersin Kategorisi Alanına Uygun Temel Öğretim Dersin Amacı Giving information about the energy metabolism in living systems Dersin İçeriği Bioenergetics principles and laws of thermodynamics, free energy (G) change, the relationship between free energy change and equilibrium constant, standard and free energy changes in non-standard conditions, high energy compounds and phosphoryl group transfer, phosphodiester bond and ATP, Sequential reactions and additivity of the free energy, biological oxidation-reduction reactions, the standard electrode potential and Nerns equation, FAD and NAD (P) related to oxidation-reduction reactions, electron transport chain and inhibitors, entry and hypotheses to oxidative phosphorylation, metabolism and ATP production: glycolysis the oxidation of fatty acids and ATP production.
 Dersin Öğrenme Çıktıları Öğretim Yöntemleri Ölçme Yöntemleri 1 - Learning the energy metabolism and related calculations 1 - A - C - 2 - 1 - 2 - 3 - A -
 Öğretim Yöntemleri: 1:Lecture 2:Question-Answer 3:Discussion Ölçme Yöntemleri: A:Testing C:Homework

#### Ders Akışı

Hafta Konular ÖnHazırlık
1 Definition and types of energy
2 System, the environment and the universe; open, closed and isolated systems
3 The laws of thermodynamics and metabolism
4 Endothermic, exothermic; endergonik and Exergonic reactions
5 Coupling of exergonic reaction with endergonik reaction
6 ATP and other high energy chemical bonds containing biomolecules
7 Midterm exam
8 The relationship between the free energy and Enthalpy, entropy; Gibbs free energy equation
9 the relationship between free energy and product / substrate concentration ratio
10 Bioenergetics and high energy molecules
11 High-energy compounds and energy relationships
12 The relationship between free energy and equilibrium constant
13 Free energy change and oxidation-reduction potential
14 Enzymes and coenzymes which are working in the oxidation-reduction reaction of

#### Kaynaklar

Ders Notu

1. Lawrence A. Kaplan, Amadeo J. Pesce Teory Analysis Correlations Clinical Chemistry. Mosby ELSEVIER, Indiana, 2010.
2. Rex Montgomery, Thomas W. Conway, Arthur A. Spector Biyokimya olgu sunumlu yaklaşım. Çeviri editörü: Nilgün Altan Palme Yayıncılık. Ankara, 2000.
3. Robert K. Murray, Daryl K. Granner, Peter A. Mayes, Victor V. Rodwell Harper biyokimya, Çeviri editörü: Nurten Dikmen, Tuncay Özgünen. Nobel Tıp Kitabevi Ankara, 2004
4. Robert K Murray, David A. BENDER. Harper’s Illustrated biochemistry 28TH, Mc Graw Hill Toronto 2009

Ders Kaynakları

#### Dersin Program Çıktılarına Katkısı

No Program Öğrenme Çıktıları KatkıDüzeyi
1 2 3 4 5
1 Sutudent has detailed biomolecules and metabolic information; uses this information and develops X
2 Knows and uses the specific equipment and tools of Biochemistry X
3 Knows and uses basic laboratory knowledge such as Laboratory safety, biochemical methods X
4 Reachs their printed and electronic information sources and follows the developments in the Biochemistry and related fields X
5 Theoretical knowledge and critical thinking skills are applied to specific work areas to plan related experiments X
6 present a seminar on a topic of current biochemistry X
7 Reads, understands, interprets, and criticizes an article in the field of biochemistry, X

#### Değerlendirme Sistemi

YARIYIL İÇİ ÇALIŞMALARI SIRA KATKI YÜZDESİ
AraSinav 1 70
Odev 1 20
KisaSinav 1 10
Toplam 100
Yıliçinin Başarıya Oranı 50
Finalin Başarıya Oranı 50
Toplam 100

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