| Ders Adı | Kodu | Yarıyıl | T+U Saat | Kredi | AKTS |
|---|---|---|---|---|---|
| Cancer Molecular Bıology | BMM 528 | 0 | 3 + 0 | 3 | 6 |
| Ön Koşul Dersleri | |
| Önerilen Seçmeli Dersler | |
| Dersin Dili | Türkçe |
| Dersin Seviyesi | YUKSEK_LISANS |
| Dersin Türü | Seçmeli |
| Dersin Koordinatörü | Doç.Dr. GAMZE GÜNEY ESKİLER |
| Dersi Verenler | Doç.Dr. GAMZE GÜNEY ESKİLER, |
| Dersin Yardımcıları | |
| Dersin Kategorisi | Alanına Uygun Öğretim |
| Dersin Amacı | Learning cancer cell biology at the molecular level |
| Dersin İçeriği | In the content of this course; Genetic and epigenetic changes that occur in cancer, cancer-causing viruses, oncogenes and proteins, tumor suppressor genes and their characteristics features, cancer types, metastasis, carcinogenic substances, molecular mechanisms specific to cancer types, cancer treatment methods and their relationship with molecular signaling pathways and innovative treatment methods |
| # | Ders Öğrenme Çıktıları | Öğretim Yöntemleri | Ölçme Yöntemleri |
|---|---|---|---|
| 1 | Describe cancer cell biology | Lecture, Question-Answer, Discussion, | Testing, Homework, |
| 2 | Understand the role of genetic anomalies in cancer development | Discussion, Question-Answer, Lecture, | Homework, Testing, |
| 3 | Explain epigenetic and genetic changes in tumor development | Discussion, Question-Answer, Lecture, | Homework, Testing, |
| 4 | Explain tumor suppressor genes and their molecular mechanisms | Discussion, Question-Answer, Lecture, | Homework, Testing, |
| 5 | Describe the types of cell death | Discussion, Question-Answer, Lecture, | Homework, Testing, |
| 6 | Discussion, Question-Answer, Lecture, | Homework, Testing, |
| Hafta | Ders Konuları | Ön Hazırlık |
|---|---|---|
| 1 | Cell and its properties | |
| 2 | Cell cycle and control | |
| 3 | Cancer and its characteristics | |
| 4 | The role of genes in cancer development | |
| 5 | Mechanisms of transformation of protoncogenes into oncogenes | |
| 6 | Cancer and epigenetic changes | |
| 7 | Carcinogens and Oncogenic Viruses | |
| 8 | Metastasis and angiogenesis | |
| 9 | Cell death types | |
| 10 | Programmed cell death | |
| 11 | Hereditary cancer types and their molecular mechanisms | |
| 12 | Cancer and gene therapy | |
| 13 | Cancer and immunotherapy | |
| 14 | Current approaches in cancer treatment |
| Kaynaklar | |
|---|---|
| Ders Notu | |
| Ders Kaynakları | Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Keith Roberts, Peter Walter. Molecular Biology of the Cell (Ed.6th), Garland Science, USA, 2014. Tom Strachan, Andrew Read, Human Molecular Genetics (Ed.4th), 2010. The Biology of Cancer 2nd edition by Weinberg, Robert A. (2013) |
| Sıra | Program Çıktıları | Katkı Düzeyi | |||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | An understanding of integrated knowledge of science and engineering in the biomedical issues. | X | |||||
| 2 | The capability to apply advanced mathematics to solve the problems at the interface of engineering and biology | ||||||
| 3 | The ability to carry out measurements on living systems and interpret the obtained data | X | |||||
| 4 | An ability to function on multi-disciplinary teams | X | |||||
| 5 | Addressing the problems associated with both living and non-living materials and systems | X | |||||
| 6 | Proficiency in the use of modern techniques, tools, procedures, and knowledge useful in the definition and solution of problems in biomedical engineering area. | ||||||
| Değerlendirme Sistemi | |
|---|---|
| Yarıyıl Çalışmaları | Katkı Oranı |
| 1. Ara Sınav | 50 |
| 1. Ödev | 50 |
| Toplam | 100 |
| 1. Yıl İçinin Başarıya | 60 |
| 1. Final | 40 |
| Toplam | 100 |
| AKTS - İş Yükü Etkinlik | Sayı | Süre (Saat) | Toplam İş Yükü (Saat) |
|---|---|---|---|
| Course Duration (Including the exam week: 16x Total course hours) | 16 | 3 | 48 |
| Hours for off-the-classroom study (Pre-study, practice) | 16 | 2 | 32 |
| Mid-terms | 1 | 25 | 25 |
| Assignment | 1 | 20 | 20 |
| Final examination | 1 | 25 | 25 |
| Toplam İş Yükü | 150 | ||
| Toplam İş Yükü / 25 (Saat) | 6 | ||
| Dersin AKTS Kredisi | 6 | ||