Course Name Code Semester T+U Hours Credit ECTS
Free Radicals and Defense Systems In Biology TBK 507 0 3 + 1 4 6
Precondition Courses
Recommended Optional Courses
Course Language Turkish
Course Level yuksek_lisans
Course Type Optional
Course Coordinator Prof.Dr. MEHMET AKDOĞAN
Course Lecturers
Course Assistants
Course Category Available Basic Education in the Field
Course Objective Giving information about free radicals and defense systems in biology
Course Content Free radical concept and definition of free radicals, free radicals sources (physiological and pathological), the overall effect of free radicals, pathology caused by free radicals, free nitrogen compounds, NO formation and effects, peroxy nitrite formation and effects and mechanisms of free radical formation and phagocytosis of neutrophils, antioxidant systems, and mechanisms of intracellular antioxidants, antioxidants and intracellular mechanism of action, pharmacological antioxidants, investigation of the article on the subject
# Course Learning Outcomes Teaching Methods Assessment Methods
1 Learn general concepts of free radicals and antioxidants. Lecture, Testing, Homework,
2 Understand the relationship between free radical damage and disease. Lecture, Testing, Homework,
3 Learn the antioxidant defense system. Lecture, Testing, Homework,
Week Course Topics Preliminary Preparation
1 Defining the concept of free radicals
2 Sources of free radicals (physiological and pathological)
3 General effects of free radicals
4 Serbest radikallerin neden olduğu patolojiler
5 Free nitrogen compounds
6 NO formation and effects
7 Midterm exam
8 Peroxy nitrite formation and effects
9 Mechanisms of free radical formation and phagocytosis in neutrophil s
10 Antioxidant systems
11 Intracellular antioxidants and mechanisms of action
12 Intracellular antioxidants and mechanisms of action
13 Pharmacological antioxidants
14 Investigation of the article on the subject
Course Notes 1. Robert K. Murray, Daryl K. Granner, Peter A. Mayes, Victor V. Rodwell Harper biyokimya, Çeviri editörü: Nurten Dikmen, Tuncay Özgünen. Nobel Tıp Kitabevi Ankara, 2004<br>2. İdris Akkuş. Serbest Radikaller ve Fizyopatolojik Etkiler. Mimoza Konya, 1995
Course Resources
Order Program Outcomes Level of Contribution
1 2 3 4 5
1 Sutudent has detailed biomolecules and metabolic information; uses this information and develops X
2 Knows and uses the specific equipment and tools of Biochemistry X
3 Knows and uses basic laboratory knowledge such as Laboratory safety, biochemical methods X
4 Reachs their printed and electronic information sources and follows the developments in the Biochemistry and related fields X
5 Theoretical knowledge and critical thinking skills are applied to specific work areas to plan related experiments X
6 present a seminar on a topic of current biochemistry X
7 Reads, understands, interprets, and criticizes an article in the field of biochemistry, X
Evaluation System
Semester Studies Contribution Rate
1. Ara Sınav 70
1. Ödev 20
1. Kısa Sınav 10
Total 100
1. Final 50
1. Yıl İçinin Başarıya 50
Total 100
ECTS - Workload Activity Quantity Time (Hours) Total Workload (Hours)
Course Duration (Including the exam week: 16x Total course hours) 16 2 32
Hours for off-the-classroom study (Pre-study, practice) 16 6 96
Mid-terms 1 6 6
Final examination 1 10 10
Total Workload 144
Total Workload / 25 (Hours) 5.76
dersAKTSKredisi 6