Course Name Code Semester T+U Hours Credit ECTS
Biochemical Calculations TBK 504 0 3 + 1 4 6
Precondition Courses
Recommended Optional Courses
Course Language Turkish
Course Level yuksek_lisans
Course Type Optional
Course Coordinator Prof.Dr. MEHMET AKDOĞAN
Course Lecturers
Course Assistants
Course Category
Course Objective Giving the biochemical method of calculation
Course Content pH and buffer systems, ionic strength, normality, molarity,% solutions.
# Course Learning Outcomes Teaching Methods Assessment Methods
1 Learn about the Solution Definition Lecture, Testing, Homework,
2 Understand the properties of the solution Lecture, Testing, Homework,
3 Learn about dissolution event (polar-nonpolar) Lecture, Testing, Homework,
4 Learn the factors affecting the resolution Lecture, Testing, Homework,
5 Learn the concentration units and definitions Lecture, Testing, Homework,
6 Learn the concentration units and definitions. Lecture, Testing, Homework,
7 Learn acid-base concepts. Lecture, Testing, Homework,
8 Understand the equilibrium constant Lecture, Testing, Homework,
9 Learn the ionization balance. Lecture, Testing, Homework,
10 learns how to calculate the concentration of the ions present in solution Lecture, Testing, Homework,
11 "p" function is learned.
Week Course Topics Preliminary Preparation
1 Aqueous solution:Definition, properties and types of solution
2 Dissolution-Resolution: Dissolution of ionic and covalent (polar-nonpolar) particules
3 Factors affecting the resolution; temperature, pressure, solvent type. Exothermic and endothermic dissolution.
4 Concentration Units1: % concentrations and osmolarity Molarite-osmolality, molality-osmolality; isotonic, hypotonic and hypertonic solutions.
5 Concentration Units 2: Normality, equivalent grams and ionic strength calculations
6 Chemical reactions and equilibrium, equilibrium of constant and rates of reaction
7 Midterm exam
8 Acids and Bases: Definition of Acid-base, strong and weak acids and bases; chemical properties of the acid and base
9 Ionization of water: Kd and Ks of Water, calculation of H + and OH- ion concentration of water
10 The calculation of H + and OH- concentration in strong and weak acid-base , degree of ionization.
11 pH and pOH: pH and pOH value of water; pH scale (criteria), calculation of pH and pOH related to strong-weak acid and base
12 Neutralization Reactions: pH and pOH calculations in acid-base mixture, titration curves
13 Amino acids of the ionization, calculations of isoelectric spot
14 Hydrolysis and salts: the relationship between Ka and Kb constants for weak acids and bases
Course Notes 1. Lawrence A. Kaplan, Amadeo J. Pesce Teory Analysis Correlations Clinical Chemistry. Mosby ELSEVIER, Indiana, 2010.<br>2. Carl A. Burtis, Edward R. Ashwood. Tietz Klinik kimyada temel ilkeler. Çeviri editörü Prof Dr Diler Aslan Palme yayıncılık, Ankara, 2005.
Course Resources
Order Program Outcomes Level of Contribution
1 2 3 4 5
1 Sutudent has detailed biomolecules and metabolic information; uses this information and develops X
2 Knows and uses the specific equipment and tools of Biochemistry X
3 Knows and uses basic laboratory knowledge such as Laboratory safety, biochemical methods X
4 Reachs their printed and electronic information sources and follows the developments in the Biochemistry and related fields X
5 Theoretical knowledge and critical thinking skills are applied to specific work areas to plan related experiments X
6 present a seminar on a topic of current biochemistry X
7 Reads, understands, interprets, and criticizes an article in the field of biochemistry, X
Evaluation System
Semester Studies Contribution Rate
1. Ara Sınav 70
1. Ödev 20
1. Kısa Sınav 10
Total 100
1. Final 50
1. Yıl İçinin Başarıya 50
Total 100
ECTS - Workload Activity Quantity Time (Hours) Total Workload (Hours)
Course Duration (Including the exam week: 16x Total course hours) 16 2 32
Hours for off-the-classroom study (Pre-study, practice) 16 6 96
Mid-terms 1 6 6
Final examination 1 10 10
Total Workload 144
Total Workload / 25 (Hours) 5.76
dersAKTSKredisi 6