| Ders Adı | Kodu | Yarıyıl | T+U Saat | Kredi | AKTS |
|---|---|---|---|---|---|
| Enzymatıc Reactıon Mechanısms | KIM 544 | 0 | 3 + 0 | 3 | 6 |
| Ön Koşul Dersleri | |
| Önerilen Seçmeli Dersler | |
| Dersin Dili | Türkçe |
| Dersin Seviyesi | YUKSEK_LISANS |
| Dersin Türü | Seçmeli |
| Dersin Koordinatörü | Prof.Dr. GÜLNUR ARABACI |
| Dersi Verenler | Prof.Dr. GÜLNUR ARABACI, |
| Dersin Yardımcıları | |
| Dersin Kategorisi | Diğer |
| Dersin Amacı | Aid to understand how mechanisms of enzymes which catalyze the biochemical reactions are important in living organisms and inform about how important enzymes in biochemistry, medicine, drug, agriculture, food and biotechnology. |
| Dersin İçeriği | Properties of enzymes, kinetics and chemical mechanisms of enzyme catalyzed reactions, identification of active centers in enzymes, chemical structure of enzyme catalysis, group transfer reactions catalyzed by enzymes, enzymatic oxidation and reduction reactions, elimination reactions catalyzed by enzymes, enzyme inhibitions, applications of enzymes. |
| # | Ders Öğrenme Çıktıları | Öğretim Yöntemleri | Ölçme Yöntemleri |
|---|---|---|---|
| 1 | Classifies enzymes and their functions | Lecture, Question-Answer, | Testing, Homework, |
| 2 | Questions the biosynthesis of enzymatic mechanisms. | Lecture, Question-Answer, | Testing, Homework, |
| 3 | Practices enzyme kinetics | Lecture, Question-Answer, Problem Solving, | Testing, Homework, |
| 4 | Identifies the elimination and transformation reactions catalyzed by enzymes | Lecture, Question-Answer, | Testing, Homework, |
| 5 | Identifies the enzymatic redox reactions . | Lecture, Question-Answer, | Testing, Homework, |
| 6 | Interprets the working systems of enzymes in living organisms | Lecture, Question-Answer, | Testing, Homework, |
| Hafta | Ders Konuları | Ön Hazırlık |
|---|---|---|
| 1 | Introduction, classifications and structures of enzymes | |
| 2 | Properties and biosynthesis of enzymes | |
| 3 | Enzyme kinetics | |
| 4 | Kinetic and chemical mechanisms of enzyme catalyzed reactions | |
| 5 | Group transferred reaction mechanisms catalyzed by enzymes | |
| 6 | Enzymatic oxidation and reduction reaction mechanisms | |
| 7 | Enzymatic elimination reactions and their mechanisms | |
| 8 | Enzymatic addition reactions | |
| 9 | MIDTERM EXAM | |
| 10 | Enzymatic isomerization and rearrangement reactions | |
| 11 | Enzymatic reactions of carboxyl group eliminations from other groups | |
| 12 | Enzymatic carboxylation reactions | |
| 13 | Aldol ve Claisen condensation reactions catalyzed by enzymes | |
| 14 | Phosphate group transferred reactions |
| Kaynaklar | |
|---|---|
| Ders Notu | |
| Ders Kaynakları | |
| Sıra | Program Çıktıları | Katkı Düzeyi | |||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | In addition to expanding and making deeper the knowledge established on undergraduate education in a same or different area, reaches the knowledge by doing research and also improves his or her knowledge to the expertise level by doing evaluation and practice. | X | |||||
| 1 | In addition to expanding and making deeper the knowledge established on undergraduate education in a same or different area, reaches the knowledge by doing research and also improves his or her knowledge to the expertise level by doing evaluation and practice. | X | |||||
| 2 | Utilizing incomplete or limited data in his or her study area expands the knowledge by experimental methods and use those obtained knowledge by scientific, social and ethical responsibility. | X | |||||
| 2 | Utilizing incomplete or limited data in his or her study area expands the knowledge by experimental methods and use those obtained knowledge by scientific, social and ethical responsibility. | X | |||||
| 3 | - Constructs a problem with his/her adviser and develops a solution method and by evaluating the results apply them if it is necessary in his/ her area. | X | |||||
| 3 | - Constructs a problem with his/her adviser and develops a solution method and by evaluating the results apply them if it is necessary in his/ her area. | ||||||
| 4 | -Transfer the current developments and his/her studies to the other related or nonrelated groups as written, orally and visually. | ||||||
| 4 | -Transfer the current developments and his/her studies to the other related or nonrelated groups as written, orally and visually. | ||||||
| 5 | - Develops new strategic approach and produces solutions in unexpected and complicated situations in his or her area of practice. | X | |||||
| 5 | - Develops new strategic approach and produces solutions in unexpected and complicated situations in his or her area of practice. | X | |||||
| 6 | - Develops strategic and practice plans and evaluates the obtained results within the framework of quality process in his or her study area. | X | |||||
| 6 | - Develops strategic and practice plans and evaluates the obtained results within the framework of quality process in his or her study area. | X | |||||
| 7 | - Has written communication ability in one of well known foreign languages (“European Language Portfolio Global Scale”, Level A1). | ||||||
| 7 | - Has written communication ability in one of well known foreign languages (“European Language Portfolio Global Scale”, Level A1). | ||||||
| 8 | -Has knowledge for software and hardware about computers and uses data processing. | ||||||
| 8 | -Has knowledge for software and hardware about computers and uses data processing. | X | |||||
| 9 | Protecting scientific, social, and ethical values, teaches and controls these values in the steps of collection, evaluation and announcement of data in the international arena. | ||||||
| 9 | Protecting scientific, social, and ethical values, teaches and controls these values in the steps of collection, evaluation and announcement of data in the international arena. | ||||||
| 10 | - Applies his or her digested knowledge and problem solving ability in advanced studies. | ||||||
| Değerlendirme Sistemi | |
|---|---|
| Yarıyıl Çalışmaları | Katkı Oranı |
| 1. Ara Sınav | 50 |
| 1. Ödev | 20 |
| 1. Performans Görevi (Seminer) | 20 |
| 1. Kısa Sınav | 10 |
| Toplam | 100 |
| 1. Yıl İçinin Başarıya | 50 |
| 1. Final | 50 |
| Toplam | 100 |
| AKTS - İş Yükü Etkinlik | Sayı | Süre (Saat) | Toplam İş Yükü (Saat) |
|---|---|---|---|
| Course Duration (Including the exam week: 16x Total course hours) | 16 | 3 | 48 |
| Hours for off-the-classroom study (Pre-study, practice) | 16 | 3 | 48 |
| Mid-terms | 1 | 15 | 15 |
| Assignment | 1 | 10 | 10 |
| Performance Task (Seminar) | 1 | 10 | 10 |
| Final examination | 1 | 20 | 20 |
| Quiz | 1 | 10 | 10 |
| Toplam İş Yükü | 161 | ||
| Toplam İş Yükü / 25 (Saat) | 6,44 | ||
| Dersin AKTS Kredisi | 6 | ||